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Chemical Structure : 4-Hydroxytamoxifen
Catalog No.: PC-70134Not For Human Use, Lab Use Only.
A selective estrogen receptor modulator (SERM) and the major active metabolite of tamoxifen.
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A selective estrogen receptor modulator (SERM) and the major active metabolite of tamoxifen; exhibits more potent estrogen agonist/antagonist activity and can inhibit MCF-7 and MDA-MB-231 cell proliferation with IC50 values of 27 and 18 uM, respectively.
Breast Cancer
Phase 2 Clinical
| M.Wt | 387.5139 | |
| Formula | C26H29NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Mansel R, et al. Breast Cancer Res Treat. 2007 Dec;106(3):389-97.
2. Desta Z, et al. J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75.
3. Seeger H, et al. Horm Metab Res. 2004 May;36(5):277-80.
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