4-octyl itaconate | NRF2 activator | Probechem Biochemicals

Chemical Structure : 4-octyl itaconate

CAS No.: 3133-16-2

4-octyl itaconate (4-OI)

Catalog No.: PC-22348Not For Human Use, Lab Use Only.

4-Octyl Itaconate (4-OI) is a cell-permeable Itaconate derivative, activates Nrf2 via alkylation of KEAP1, is protective against lipopolysaccharide-induced lethality in vivo and decreases cytokine production.

Packing	Price	Stock
10 mg (Free Sample)	$18	In stock
50 mg	$88	In stock
100 mg	$128	In stock
250 mg	$198	In stock
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Biological Activity

Physicochemical Properties

M.Wt	242.32
Formula	C13H22O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Methylene-4-(octyloxy)-4-oxobutanoic acid

References

1. Mills EL, et al. Nature. 2018 Apr 5;556(7699):113-117.

2. Olagnier D, et al. Nat Commun. 2018 Aug 29;9(1):3506.

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4-octyl itaconate (4-OI)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

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