4BPPNit

Chemical Structure : 4BPPNit

Catalog No.: PC-73362Not For Human Use, Lab Use Only.

4BPPNit is a small molecule enhancer of glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.

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Biological Activity

4BPPNit is a small molecule enhancer of glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.
4BPPNit augments functional glycosylation of α-dystroglycan in human FKRP-iPSC-derived neural stem cells.
4BPPNit induces upregulation of LARGE1 gene expression.

Physicochemical Properties

M.Wt	337.235
Formula	C14H13BrN2OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-bromophenyl)-6-ethylsulfanyl-2-oxo-3,4-dihydro-1H-pyridine-5-carbonitrile

References

1. Jihee Kim, et al. EMBO Rep. 2019 Nov 5;20(11):e47967.

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4BPPNit

Biological Activity

Physicochemical Properties

References

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