4BPPNit

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Chemical Structure : 4BPPNit

Catalog No.: PC-73362Not For Human Use, Lab Use Only.

4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.
4BPPNit augments functional glycosylation of α‐dystroglycan in human FKRP‐iPSC‐derived neural stem cells.
4BPPNit induces upregulation of LARGE1 gene expression.

Physicochemical Properties

M.Wt	337.235
Formula	C14H13BrN2OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-bromophenyl)-6-ethylsulfanyl-2-oxo-3,4-dihydro-1H-pyridine-5-carbonitrile

References

1. Jihee Kim, et al. EMBO Rep. 2019 Nov 5;20(11):e47967.

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4BPPNit

Biological Activity

Physicochemical Properties

References

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