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4BPPNit

Chemical Structure : 4BPPNit

CAS No.: 197569-89-4

4BPPNit

Catalog No.: PC-73362Not For Human Use, Lab Use Only.

4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.
    4BPPNit augments functional glycosylation of α‐dystroglycan in human FKRP‐iPSC‐derived neural stem cells.
    4BPPNit induces upregulation of LARGE1 gene expression.

    Physicochemical Properties

    M.Wt 337.235
    Formula C14H13BrN2OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(4-bromophenyl)-6-ethylsulfanyl-2-oxo-3,4-dihydro-1H-pyridine-5-carbonitrile

    References

    1. Jihee Kim, et al. EMBO Rep. 2019 Nov 5;20(11):e47967.

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