6H05 | KRAS G12C inhibitor| Probechem Biochemicals

Chemical Structure : 6H05

6H05 (K-Ras inhibitor)

Catalog No.: PC-43021Not For Human Use, Lab Use Only.

6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C), an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors..

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Biological Activity

6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C), an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors.

Physicochemical Properties

M.Wt	476.1191
Formula	C20H30ClN3O2S3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Piperidinecarboxamide, 1-[2-[(4-chlorophenyl)thio]acetyl]-N-[2-[[2-(dimethylamino)ethyl]dithio]ethyl]-

References

1. Ostrem JM, et al. Nature. 2013 Nov 28;503(7477):548-51.

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6H05 (K-Ras inhibitor)

Biological Activity

Physicochemical Properties

References

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