6K465 is a potent selective Aurora A (AURKA) inhibitor, effectively inhibits cancer cells overexpressing c-MYC- and/or N-MYC.
6K465 reduces levels of c-MYC and N-MYC oncoproteins more potently than alisertib.
6K465 dispalys potent antiproliferative effect an sensitivity against cell lung cancer (SCLC) and breast cancer (BC) cell lines with high protein levels of c-MYC and/or N-MYC.
