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A-3190

Chemical Structure : A-3190

CAS No.:

A-3190 (A3190)

Catalog No.: PC-26874Not For Human Use, Lab Use Only.

A-3190 is a potent, selective, brain-penetrant CD38 inhibitor with IC50 of 7.2 nM and 1.2 nM for human and mouse CD38 respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A-3190 is a potent, selective, brain-penetrant CD38 inhibitor with IC50 of 7.2 nM and 1.2 nM for human and mouse CD38 respectively.

Physicochemical Properties

M.Wt 383.44
Formula C17H13N5O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(1-(cyclopropylsulfonyl)-1H-pyrazol-4-yl)-7-(pyridin-4-yl)thieno[3,2-d]pyrimidine

References

1. Shiroodi R, et al. J Med Chem. 2026 May 24. doi: 10.1021/acs.jmedchem.6c00171.

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