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A-794282

Chemical Structure : A-794282

CAS No.: 869802-44-8

A-794282 (A794282)

Catalog No.: PC-28187Not For Human Use, Lab Use Only.

A-794282 is a potent and selective mGlu1 receptor (mGluR1) antagonist with IC50 of 3 nM, demonstrates full efficacy in various in vivo animal pain models.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A-794282 is a potent and selective mGlu1 receptor (mGluR1) antagonist with IC50 of 3 nM, demonstrates full efficacy in various in vivo animal pain models.

Physicochemical Properties

M.Wt 350.44
Formula C19H18N4OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

9-(Dimethylamino)-3-(4-ethylphenyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one

References

1. Zheng GZ, et al. J Med Chem. 2005 Nov 17;48(23):7374-88.

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