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A-8531

Chemical Structure : A-8531

CAS No.:

A-8531 (A8531)

Catalog No.: PC-26873Not For Human Use, Lab Use Only.

A-8531 is a potent, selective, peripheral CD38 inhibitor with IC50 of 0.4 nM and 3.6 nM for human and mouse CD38 respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A-8531 is a potent, selective, peripheral CD38 inhibitor with IC50 of 0.4 nM and 3.6 nM for human and mouse CD38 respectively.

Physicochemical Properties

M.Wt 384.44
Formula C22H20N6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(2-amino-3-(pyridin-4-yl)imidazo[1,2-b]pyridazin-6-yl)-N-cyclopropyl-N-methylbenzamide

References

1. Shiroodi R, et al. J Med Chem. 2026 May 24. doi: 10.1021/acs.jmedchem.6c00171.

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