A2AR antagonist P400

Chemical Structure : A2AR antagonist P400

Catalog No.: PC-26044Not For Human Use, Lab Use Only.

A2AR antagonist P400 is a highly potent, selective adenosine A2A receptor (A2AR) antagonist with Ki of 5.3 fM (human cloned A2AR), ameliorates EAE symptoms by attenuating neuroinflammation and demyelination.

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Biological Activity

Physicochemical Properties

M.Wt	353.40
Formula	C17H15N5O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(furan-2-yl)-N5-(3-methoxybenzyl)thiazolo[5,4-d]pyrimidine-5,7-diamine

References

1. M Morozzi, et al. Neuropharmacology. 2026 May 1:288:110857.

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A2AR antagonist P400

Biological Activity

Physicochemical Properties

References

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