A71915 | NPRA inhibitor | Probechem Biochemicals

Chemical Structure : A71915

CAS No.: 132956-87-7

A71915 (A 71915 )

Catalog No.: PC-21725Not For Human Use, Lab Use Only.

A71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist with pKi of 9.18.

Packing	Price	Stock
2 mg	$228	In stock
5 mg	$368	In stock
10 mg	$588	In stock
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Biological Activity

A71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist with pKi of 9.18.
A71915 displaces [125I]ANP dose dependently with Ki of 0.65 nM against rat ANP-induced cGMP production in NB-OK-1 cells.
A71915 suppresses atrial natriuretic peptide (ANP)-stimulated cyclic GMP elevation.

Physicochemical Properties

M.Wt	1613.95
Formula	C69H116N26O15S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[Arg6, Cha8]ANP-(6-15)-D-Tic-Arg-Cys-NH2

References

1. Delporte C, et al. Eur J Pharmacol. 1992;224(2-3):183-188.

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A71915 (A 71915 )

Biological Activity

Physicochemical Properties

References

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