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Chemical Structure : A71915
CAS No.: 132956-87-7
Catalog No.: PC-21725Not For Human Use, Lab Use Only.
A71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist with pKi of 9.18.
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A71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist with pKi of 9.18.
A71915 displaces [125I]ANP dose dependently with Ki of 0.65 nM against rat ANP-induced cGMP production in NB-OK-1 cells.
A71915 suppresses atrial natriuretic peptide (ANP)-stimulated cyclic GMP elevation.
| M.Wt | 1613.95 | |
| Formula | C69H116N26O15S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
[Arg6, Cha8]ANP-(6-15)-D-Tic-Arg-Cys-NH2 |
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1. Delporte C, et al. Eur J Pharmacol. 1992;224(2-3):183-188.
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