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AAL(S)

Chemical Structure : AAL(S)

CAS No.: 1823156-89-3

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AAL(S) (PP2A activator AAL(S))

Catalog No.: PC-35654Not For Human Use, Lab Use Only.

AAL(S) is the chiral deoxy analog of the FDA approved drug FTY720, has been shown to inhibit proliferation and apoptosis in several cancer cell lines by activating protein phosphatase 2A (PP2A).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AAL(S) is the chiral deoxy analog of the FDA approved drug FTY720, has been shown to inhibit proliferation and apoptosis in several cancer cell lines by activating protein phosphatase 2A (PP2A).

    Physicochemical Properties

    M.Wt 307.478
    Formula C19H33NO2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-2-amino-2-methyl-4-(4-(octyloxy)phenyl)butan-1-ol

    References

    1. Toop HD, et al. Org Biomol Chem. 2016 May 18;14(20):4605-16.

    2. Nair PM, et al. Allergy. 2017 Dec;72(12):1891-1903.

    3. Rahman MM, et al. Cell Signal. 2016 Apr;28(4):325-34.

    4. Rahman MM, et al. Sci Rep. 2015 May 18;5:10063.

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