ABBV-3221 | CFTR corrector | Probechem Biochemicals

Chemical Structure : ABBV-3221

Catalog No.: PC-38707Not For Human Use, Lab Use Only.

ABBV-3221 (GLPG-3221) is a highly potent CFTR corrector with HBE-TECC EC50 of 105 nM.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ABBV-3221 (GLPG-3221) is a highly potent CFTR corrector with HBE-TECC EC50 of 105 nM.

M.Wt	578.629
Formula	C30H37F3N2O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3R,4S,5S)-3-(tert-butyl)-4-((2-methoxy-5-(trifluoromethyl)pyridin-3-yl)methoxy)-1-((S)-tetrahydro-2H-pyran-2-carbonyl)-5-(o-tolyl)pyrrolidine-2-carboxylic acid

1. Wang X, et al. J Med Chem. 2018 Feb 22;61(4):1436-1449.

2. Scanio MJC, et al. ACS Med Chem Lett. 2019 Oct 31;10(11):1543-1548.