Tegeprotafib (ABBV-CLS-579) | PTP1B/PTPN2 inhibitor

Chemical Structure : ABBV-CLS-579

CAS No.: 2407610-46-0

ABBV-CLS-579 (Tegeprotafib)

Catalog No.: PC-23059Not For Human Use, Lab Use Only.

Tegeprotafib (ABBV-CLS-579) is a potent, selective orally active PTP1B/PTPN2 inhibitor with IC50 of 4.4 nM and 1-10 nM against PTPN2 and PTP1B, respectively

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5 mg	$528	In stock
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Biological Activity

Tegeprotafib (ABBV-CLS-579) is a potent, selective orally active PTP1B/PTPN2 inhibitor with IC50 of 4.4 nM and 1-10 nM against PTPN2 and PTP1B, respectively

Physicochemical Properties

M.Wt	326.30
Formula	C13H11FN2O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,2,5-Thiadiazolidin-3-one, 5-(1-fluoro-3-hydroxy-7-methoxy-2-naphthalenyl)-, 1,1-dioxide

References

1. Patent WO2019246513A1.

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ABBV-CLS-579 (Tegeprotafib)

Biological Activity

Physicochemical Properties

References

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