ABC transporter modulator-3 | ABCC6 modulator

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Chemical Structure : ABC transporter modulator-3

ABC transporter modulator-3 (ABCC6 positive functional modulator)

Catalog No.: PC-28078Not For Human Use, Lab Use Only.

ABC transporter modulator-3 is a potent, selective positive functional modulator (PFM) of ATP-binding cassette (ABC) transporter ABCC6, upregulates the expression of wild-type ABCC6 with EC50 of <1 uM, shows high selectivity over ABCB4, ABCA4 P1380L and ACBC2.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ABC transporter modulator-3 is a potent, selective positive functional modulator (PFM) of ATP-binding cassette (ABC) transporter ABCC6, upregulates the expression of wild-type ABCC6 with EC50 of <1 uM, shows high selectivity over ABCB4, ABCA4 P1380L and ACBC2.

Physicochemical Properties

M.Wt	480.97
Formula	C24H21ClN4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5'-chloro-6-(mesityloxy)-[2,3'-bipyridin]-5-yl)pyridine-3-sulfonamide

References

1. Patent WO2025151724 A1 2025-07-17.

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ABC transporter modulator-3 (ABCC6 positive functional modulator)

Biological Activity

Physicochemical Properties

References

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