ABT-925 (A-437203) | D3 receptor antagonist

Chemical Structure : ABT-925

CAS No.: 220519-06-2

ABT-925 (ABT925, A-437203, Lu201640)

Catalog No.: PC-20083Not For Human Use, Lab Use Only.

ABT-925 (A-437203) is a potent selective dopamine D3 receptor antagonist with Ki of 1.6 nM, 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors.

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Biological Activity

ABT-925 (A-437203) is a potent selective dopamine D3 receptor antagonist with Ki of 1.6 nM, 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors.

Physicochemical Properties

M.Wt	456.53
Formula	C20H27F3N6OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((3-(4-(2-(tert-butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)propyl)thio)pyrimidin-4(3H)-one

References

1. Graff-Guerrero A, et al. Int J Neuropsychopharmacol. 2010 Apr;13(3):273-87.

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ABT-925 (ABT925, A-437203, Lu201640)

Biological Activity

Physicochemical Properties

References

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