| Cat. No. |
Product Name |
Information |
| PC-21084 |
Lurasidone hydrochloride
D2R antagonist
|
Lurasidone hydrochloride (SM-13496) is an atypical antipsychotic compound with potent dopamine D2 (Ki =1.68 nM) and serotonin 5-HT2A (Ki=2.03 nM) receptor-blocking activities. |
| PC-21083 |
Lurasidone
D2R antagonist
|
Lurasidone (SM-13496) is an atypical antipsychotic compound with potent dopamine D2 (Ki =1.68 nM) and serotonin 5-HT2A (Ki=2.03 nM) receptor-blocking activities. |
| PC-49147 |
ABS01-113
D3R agonist
|
(±)-ABS01-113 is a structural analog of the D3R partial agonist, (±)-VK4-40. |
| PC-47115 |
Mesdopetam hemitartrate
D3R antagonist
|
Mesdopetam (IRL790) is a novel dopamine transmission modulator and dopamine D3 receptor antagonist with Ki/IC50 of 0.09/0.41 uM. |
| PC-47114 |
Mesdopetam
D3R antagonist
|
Mesdopetam (IRL790) is a novel dopamine transmission modulator and dopamine D3 receptor antagonist with Ki/IC50 of 0.09/0.41 uM. |
| PC-47104 |
BAK4-54
D3R antagonist
|
BAK4-54 is a high affinity dopamine D3 receptor (D3R) antagonist/partial agonist withIC50 of 8.0 nM as full D3R antagonist, EC50 of 140 nM as partial D3R agonist. |
| PC-47103 |
CAB2-015
D3R antagonist
|
CAB2-015 is a high affinity dopamine D3 receptor (D3R) antagonist/partial agonist withIC50 of 7.4 nM, Ki of 0.351 nM, 45-fold selectivity over D2R. |
| PC-47102 |
(±)VK4-40
D3R agonist
|
(±)VK4-40 is a highly selective and metabolically stable D3 partial agonist, shows high affinity for D3 receptor (Ki=0.35 nM) and high selectivity for D3 over the D2 receptor. |
| PC-47101 |
R-VK4-40
D3R antagonist
|
R-VK4-40 is a highly selective, potent and orally available dopamine D3 receptor (D3R) antagonist with Ki of 6.8 nM, >1500-dold selectivity over D2R. |
| PC-47096 |
F17464
D3 antagonist
|
F17464 is a dopamine D 3 receptor preferential antagonist exhibiting high affinity for human dopamine receptor subtype 3 (hD3) (Ki=0.17 nM) and 5-HT1a (Ki=0.16 nM) and a >50 fold lower affinity for the human dopamine receptor subtype 2 short and long form (hD2s/l) (Ki=8.9 and 12.1 nM, respectively). |
| PC-38703 |
ML321
D2R antagonist
|
ML321, CAS 1596117-75-7, ML 321, D2R antagonist. ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity. |
| PC-73068 |
LY3154207
Dopamine D1 PAM
|
LY3154207 (Mevidalen, LY-3154207) is a potent, and subtype selective human dopamine D1 positive allosteric modulator (PAM) with EC50 of 3.0 nM. |
