| Cat. No. |
Product Name |
Information |
| PC-23120 |
SB-277011 hydrochloride
D3R antagonist
|
SB-277011 hydrochloride (SB277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0. |
| PC-23107 |
PF-06412562
D1R agonist
|
PF-06412562 (PF-2562, CVL-562) is a potent, selective non-catechol dopamine D1R agonist with Ki of 113 nM and EC50 of 568 nM, Emax 44%, PF-06412562 is a selective D1/D5 dopamine receptor partial agonist. |
| PC-21487 |
Nemonapride
D2R antagonist
|
Nemonapride (YM-09151-2) is a highly potent, selective dopamine D2 receptor (D2R) antagonist with Ki of 0.06 nM, also activates 5-HT1A receptor with IC50 of 34 nM, shows antipsychotic effect. |
| PC-21106 |
L-745870
D4R inhibitor
|
L-745870 (L-745,870) is is a potent, selective, brain-penetrant and orally active dopamine D4 receptor (D4R) antagonist with Ki of 0.43 nM. |
| PC-21084 |
Lurasidone hydrochloride
D2R antagonist
|
Lurasidone hydrochloride (SM-13496) is an atypical antipsychotic compound with potent dopamine D2 (Ki =1.68 nM) and serotonin 5-HT2A (Ki=2.03 nM) receptor-blocking activities. |
| PC-21083 |
Lurasidone
D2R antagonist
|
Lurasidone (SM-13496) is an atypical antipsychotic compound with potent dopamine D2 (Ki =1.68 nM) and serotonin 5-HT2A (Ki=2.03 nM) receptor-blocking activities. |
| PC-20865 |
GR 103691
D3 receptor antagonist
|
GR 103691 is a potent, selective dopamine D3 receptor antagonist with binding Ki of 0.4 nM, >100-fold selectivity over D1 and D4 receptors. |
| PC-20863 |
NGB-2904
D3 receptor antagonist
|
NGB-2904 (NGB2904) is a potent, highly selective dopamine D3 receptor (D3R) antagonist with Ki of 2.0 nM for hD3, 56-fold selectivity over hD2. |
| PC-20862 |
PG01037
D3 receptor antagonist
|
PG01037 is a potent selective dopamine D3 receptor (D3R) antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively. |
| PC-20169 |
AG-0029
D2/D3 agonist/H3 antagonist
|
AG-0029 is a highly potent agonist of dopamine D2/D3 receptor (EC50=0.08 nM) and a moderate affinity antagonis of H3 receptor (IC50=111 nM). |
| PC-20083 |
ABT-925
D3 receptor antagonist
|
ABT-925 (A-437203) is a potent selective dopamine D3 receptor antagonist with Ki of 1.6 nM, 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors. |
| PC-49576 |
(-)-GSK598809
D3 receptor antagonist
|
GSK598809 (GSK-598809) is a potent, selective dopamine D(3) receptor antagonist with Ki value of 6.2 nM, >100-fold selectivity over D2 receptor. |
