| Cat. No. |
Product Name |
Information |
| PC-23118 |
FOB02-04A
D3R agonist
|
FOB02-04A is a selective, bitopic and full agonist of dopamine 3 receptor (D3R) with Ki of 1.85 nM, 47- and 155-fold selective over D2R and D4R. |
| PC-23109 |
D5R agonist 5j
D5R agonist
|
D5R agonist 5j is a selective dopamine D5 receptor (D5R) partial agonist with EC50 of 269.7 nM, not active at the other four dopamine receptors. |
| PC-23108 |
PW0464
D1R agonist
|
PW0464 ((Rac)-Razpipadon) is a potent, selective G protein biased ligand/agonist of dopamine 1 receptor (D1R) with EC50 of 5.8 nM (Gs-cAMP), Emax of 104%. |
| PC-23107 |
PF-2562
D1R agonist
|
PF-2562 is a potent, selective non-catechol dopamine D1R agonist with Ki of 113 nM and EC50 of 568 nM. |
| PC-22633 |
FOB02-04
D3R agonist
|
FOB02-04 is a potent, selective dopamine D3 receptor (D3R) agonist with Ki of 2.84 nM, weak affinity with Ki of 106 nM for D2R. |
| PC-22235 |
Raclopride
Dopamine D2/D3 antagonist
|
Raclopride (FLA 870) is a potent, selective dopamine D2/D3 receptor antagonist, binds to D2 and D3 receptors with Ki of 1.8 nM and 3.5 nM, respectively. |
| PC-22227 |
A-77636 hydrochloride
Dopamine D1 agonist
|
A-77636 hydrochloride is a potent, selective, orally active and long acting dopamine D1 receptor agonist with Ki of 39.8 nM. |
| PC-22147 |
SCH23390 hydrochloride
Dopamine Receptor antagonist
|
SCH23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. |
| PC-21488 |
NGD-94-1
D4R inhibitor
|
NGD-94-1 is a highly potent, selective dopamine D4 receptor antagonist with Ki of 3.6 nM. |
| PC-21487 |
Nemonapride
D2R antagonist
|
Nemonapride (YM-09151-2) is a highly potent, selective dopamine D2 receptor antagonist with Ki of 0.06 nM. |
| PC-21106 |
L-745870
D4R inhibitor
|
L-745870 (L-745,870) is is a potent, selective, brain-penetrant and orally active dopamine D4 receptor (D4R) antagonist with Ki of 0.43 nM. |
| PC-21105 |
CAB-01-019
D4R inhibitor
|
CAB-01-019 is potent, selective dopamine D4 receptor (D4R) full antagonist with binding Ki of 2.2 nM, >500-fold selectivity over D2R and D3R. |
