| Cat. No. |
Product Name |
Information |
| PC-42583 |
SKF 82958
Dopamine D1 agonist, ERα agonist
|
SKF 82958 is a potent, full dopamine D1 agonist, produces characteristic anorectic effects, hyperactivity and self-administration in animals. |
| PC-45204 |
Metoclopramide
D2R antagonist
|
Metoclopramide is apotent dopamine D2 receptor antagonist with Ki of 28 nM. |
| PC-42716 |
SB-277011
D3R antagonist
|
SB-277011 (SB277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0. |
| PC-23532 |
Fenoldopam mesylate
Dopamine D1 agonist
|
Fenoldopam (SKF82526) is a potent, selective dopamine-1 (DA-1) receptor partial agonist with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells. |
| PC-23210 |
Amisulpride
D(2/3)/5-HT(7) inhibitor
|
Amisulpride (SEP-4199, DAN2163) is an N-methylated analogue of amisulpride, selective dopamine D(2/3)/5-HT(7) inhibitor, binds to the D2 receptor and 5-HT7 receptor with Ki of 1.1 nM and 44 nM respectively, shows potential for treatment of schizophrenia and other psychiatric disorders. |
| PC-23209 |
LB-102
D(2/3)/5-HT(7) inhibitor
|
LB-102 is an N-methylated analogue of amisulpride, selective dopamine D(2/3)/5-HT(7) inhibitor, binds to the D2 receptor and 5-HT7 receptor with Ki of 0.85 nM and 31 nM respectively, shows potential for treatment of schizophrenia and other psychiatric disorders. |
| PC-23120 |
SB-277011 hydrochloride
D3R antagonist
|
SB-277011 hydrochloride (SB277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0. |
| PC-23118 |
FOB02-04A
D3R agonist
|
FOB02-04A is a selective, bitopic and full agonist of dopamine 3 receptor (D3R) with Ki of 1.85 nM, 47- and 155-fold selective over D2R and D4R. |
| PC-23109 |
D5R agonist 5j
D5R agonist
|
D5R agonist 5j is a selective dopamine D5 receptor (D5R) partial agonist with EC50 of 269.7 nM, not active at the other four dopamine receptors. |
| PC-23108 |
PW0464
D1R agonist
|
PW0464 ((Rac)-Razpipadon) is a potent, selective G protein biased ligand/agonist of dopamine 1 receptor (D1R) with EC50 of 5.8 nM (Gs-cAMP), Emax of 104%. |
| PC-23107 |
PF-2562
D1R agonist
|
PF-2562 is a potent, selective non-catechol dopamine D1R agonist with Ki of 113 nM and EC50 of 568 nM. |
| PC-22633 |
FOB02-04
D3R agonist
|
FOB02-04 is a potent, selective dopamine D3 receptor (D3R) agonist with Ki of 2.84 nM, weak affinity with Ki of 106 nM for D2R. |
