| Cat. No. |
Product Name |
Information |
| PC-49149 |
(R)-ABS01-113
D3R antagonist
|
(R)-ABS01-113 is a potent, selective dopamine D3 receptor (D3R) antagonist with IC50 of 11.4 nM, binds with high affinity to D3R with Ki value of 0.34 nM. |
| PC-49148 |
(S)-ABS01-113
D3R agonist
|
(S)-ABS01-113 is a potent, highly selective and efficacious dopamine D3 receptor (D3R) partial agonist with EC50 of 7.6 nM, binds with high affinity to D3R with Ki value of 0.84 nM, >1,000-fold selectivity over D2R. |
| PC-38472 |
cis-(Z)-Flupentixol Dihydrochloride
Dopamine antagonist
|
cis-(Z)-Flupenthixol dihydrochloride is a dopamine receptor antagonist with antipsychotic effect, is a powerful antagonist of both D1 and D2 dopamine receptors. |
| PC-38470 |
WW-III-55
D3R agonist
|
WW-III-55 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 20 nM, exhibits >800-fold binding selectivity for D3R compared with the D2R. |
| PC-38469 |
OS-3-106
D3R agonist
|
OS-3-106 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 0.2 nM, exhibits 115-fold binding selectivity for D3R compared with the D2R. |
| PC-72281 |
Trazpiroben
D2/D3 antagonist
|
Trazpiroben (TAK-906) is a potent, peripherally selective D2/D3 dopamine receptor antagonist, moderate affinity for D4, and minimal for D1 and D5. |
| PC-72176 |
(–)-IHCH7041
DRD2 agonist
|
(–)-IHCH7041 is a potent, selective partial agonist at DRD2/3 and 5-HT1AR, EC50 of 1.38 nM in Gαi1–γ9 dissociation and 2.75 nM in β-arrestin2 recruitment assays, with negligible 5-HT2AR binding (>100-fold selectivity). |
| PC-72158 |
ML417
D3R agonist
|
ML417 (ML 417) is a novel potent and uniquely selective D3 dopamine receptor (D3R) full agonist with EC50 of 38 nM in β-arrestin recruitment assays. |
| PC-72157 |
CJ-1639
D3R agonist
|
CJ-1639 (CJ1639) is a potent, highly selective dopamine D3 receptor (D3R) full agonist with Ki of 0.5 nM, >5,000-fold selectivity over D1 and D2 receptors in binding assays. |
| PC-36061 |
Compound 621433144
|
Compound 621433144 (ZINC000621433144, Z3269026405) is a potent, selective full agonist of the D4 receptor with 2,500-fold subtype selectivity. |
| PC-35989 |
SK609
|
SK609 (SK-609, ES609) is a potent, selective agonist of dopamine D3 receptor with a bias towards the G-protein-dependent pathway rather than recruiting β-arrestin-2 and an EC50 value of 113.9 nM for activation of ERK1/2 phosphorylation. |
| PC-35799 |
PF-06256142
|
PF-06256142 (PF06256142) is a potent and selective orthosteric agonist of the D1 receptor with EC50 (cAMP) of 33 nM, shows exquisitely selectivity over D2. |
