Cat. No. |
Product Name |
Information |
PC-49576 |
(-)-GSK598809
D3 receptor antagonist
|
GSK598809 (GSK-598809) is a potent, selective dopamine D(3) receptor antagonist with Ki value of 6.2 nM, >100-fold selectivity over D2 receptor. |
PC-49304 |
ASP4345
D1R PAM
|
ASP4345 (ASP-4345) is a potent, selective positive allosteric modulator of the dopamine type 1 (D1) receptor that selectively binds to, and enhances the activity of, D1 receptors. |
PC-49303 |
UCM-1306
D1R PAM
|
UCM-1306 (UCM1306) is a subtype-selective, non-covalent, orally bioavailable positive allosteric modulator of dopamine D1 receptor with EC50 of 60 nM. |
PC-49149 |
(R)-ABS01-113
D3R antagonist
|
(R)-ABS01-113 is a potent, selective dopamine D3 receptor (D3R) antagonist with IC50 of 11.4 nM, binds with high affinity to D3R with Ki value of 0.34 nM. |
PC-49148 |
(S)-ABS01-113
D3R agonist
|
(S)-ABS01-113 is a potent, highly selective and efficacious dopamine D3 receptor (D3R) partial agonist with EC50 of 7.6 nM, binds with high affinity to D3R with Ki value of 0.84 nM, >1,000-fold selectivity over D2R. |
PC-38472 |
cis-(Z)-Flupentixol Dihydrochloride
Dopamine antagonist
|
cis-(Z)-Flupenthixol dihydrochloride is a dopamine receptor antagonist with antipsychotic effect, is a powerful antagonist of both D1 and D2 dopamine receptors. |
PC-38470 |
WW-III-55
D3R agonist
|
WW-III-55 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 20 nM, exhibits >800-fold binding selectivity for D3R compared with the D2R. |
PC-38469 |
OS-3-106
D3R agonist
|
OS-3-106 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 0.2 nM, exhibits 115-fold binding selectivity for D3R compared with the D2R. |
PC-72281 |
Trazpiroben
D2/D3 antagonist
|
Trazpiroben (TAK-906) is a potent, peripherally selective D2/D3 dopamine receptor antagonist, moderate affinity for D4, and minimal for D1 and D5. |
PC-72176 |
(–)-IHCH7041
DRD2 agonist
|
(–)-IHCH7041 is a potent, selective partial agonist at DRD2/3 and 5-HT1AR, EC50 of 1.38 nM in Gαi1–γ9 dissociation and 2.75 nM in β-arrestin2 recruitment assays, with negligible 5-HT2AR binding (>100-fold selectivity). |
PC-72158 |
ML417
D3R agonist
|
ML417 (ML 417) is a novel potent and uniquely selective D3 dopamine receptor (D3R) full agonist with EC50 of 38 nM in β-arrestin recruitment assays. |
PC-72157 |
CJ-1639
D3R agonist
|
CJ-1639 (CJ1639) is a potent, highly selective dopamine D3 receptor (D3R) full agonist with Ki of 0.5 nM, >5,000-fold selectivity over D1 and D2 receptors in binding assays. |