| Cat. No. |
Product Name |
Information |
| PC-70058 |
PD128907 hydrochloride
D3R agonist
|
PD128907 hydrochloride is a potent, selective and orally active agonist of dopamine D3 receptor (D3R) with Ki of 20 nM. |
| PC-70057 |
PF-219061
D3R agonist
|
PF-219061 (PF 219061, PF219061) is a potent, selective agonist of dopamine D3 receptor with EC50 of 8 nM. |
| PC-42584 |
SKF-82958 hydrobromide
Dopamine D1 agonist, ERα agonist
|
SKF-82958 hydrobromide is a potent, full dopamine D1 agonist, produces characteristic anorectic effects, hyperactivity and self-administration in animals. |
| PC-42583 |
SKF 82958
Dopamine D1 agonist, ERα agonist
|
SKF 82958 is a potent, full dopamine D1 agonist, produces characteristic anorectic effects, hyperactivity and self-administration in animals. |
| PC-45204 |
Metoclopramide
D2R antagonist
|
Metoclopramide is apotent dopamine D2 receptor antagonist with Ki of 28 nM. |
| PC-42716 |
SB-277011
D3R antagonist
|
SB-277011 (SB277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0. |
| PC-24638 |
Metopimazine
D2R antagonist
|
Metopimazine is a selective, peripherally restricted dopamine D2 receptor (D2R) antagonist, has potential for the symptomatic treatment of nausea and vomiting and chemotherapy-induced nausea and vomiting. |
| PC-24637 |
Metopimazine mesylate
D2R antagonist
|
Metopimazine mesylate (NG101) is a selective, peripherally restricted dopamine D2 receptor (D2R) antagonist, has potential for the symptomatic treatment of nausea and vomiting and chemotherapy-induced nausea and vomiting. |
| PC-24332 |
ESG-1-61
D3 receptor antagonist
|
ESG-1-61 is a potent, selective antagonist/inverse agonist of dopamine D3 receptor (D3R) with Ki of 0.73 nM, EC50 of 3.36 nM (Go activation) and4.36 nM (β-arrestin2 recruitment), show ~20-fold binding selectivity for D3 over D2 receptors. |
| PC-24331 |
ESG-1-60
D3 receptor agonist
|
ESG-1-60 is a potent, selective partial agonist of dopamine D3 receptor (D3R) with Ki of 0.14 nM, EC50 of 3.43 nM (Go activation) and 0.2 nM (β-arrestin2 recruitment), show ~20-fold binding selectivity for D3 over D2 receptors. |
| PC-24330 |
Cariprazine hydrochloride
D3 receptor agonist
|
Cariprazine (RGH-188) hydrochloride is an antipsychotic compound that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). |
| PC-24329 |
Cariprazine
D3 receptor agonist
|
Cariprazine (RGH-188) is an antipsychotic compound that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). |
