| Cat. No. |
Product Name |
Information |
| PC-21106 |
L-745870
D4R inhibitor
|
L-745870 (L-745,870) is is a potent, selective, brain-penetrant and orally active dopamine D4 receptor (D4R) antagonist with Ki of 0.43 nM. |
| PC-21105 |
CAB-01-019
D4R inhibitor
|
CAB-01-019 is potent, selective dopamine D4 receptor (D4R) full antagonist with binding Ki of 2.2 nM, >500-fold selectivity over D2R and D3R. |
| PC-20978 |
ZINC621433144
D4 agonist
|
ZINC621433144 is a Gi-biased, high-affinity full agonist of dopamine D4 receptor with Ki of 4.3 nM and cAMP EC50 of 0.18 nM. |
| PC-20865 |
GR-103691
D3 receptor antagonist
|
GR-103691 is a potent, selective dopamine D3 receptor antagonist with binding Ki of 0.4 nM, >100-fold selectivity over D1 and D4 receptors. |
| PC-20864 |
CJB 090
D3 receptor agonist
|
CJB 090 (CJB090) is a selective partial agonist of dopamine D3 receptor with binding Ki of 0.6 nM, CJB 090 is 97-fold selective for D3 receptors over D2. |
| PC-20863 |
NGB-2904
D3 receptor antagonist
|
NGB-2904 is a potent, highly selective dopamine D3 receptor antagonist with Ki of 2.0 nM for hD3, 56-fold selectivity over hD2. |
| PC-20862 |
PG01037
D3 receptor antagonist
|
PG01037 is a potent selective dopamine D3 receptor antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively. |
| PC-20169 |
AG-0029
D2/D3 agonist/H3 antagonist
|
AG-0029 is a highly potent agonist of dopamine D2/D3 receptor (EC50=0.08 nM) and a moderate affinity antagonis of H3 receptor (IC50=111 nM). |
| PC-20083 |
ABT-925
D3 receptor antagonist
|
ABT-925 (ABT925) is a potent selective dopamine D3 receptor antagonist, pproximately 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors. |
| PC-49576 |
(-)-GSK598809
D3 receptor antagonist
|
GSK598809 (GSK-598809) is a potent, selective dopamine D(3) receptor antagonist with Ki value of 6.2 nM, >100-fold selectivity over D2 receptor. |
| PC-49304 |
ASP4345
D1R PAM
|
ASP4345 (ASP-4345) is a potent, selective positive allosteric modulator of the dopamine type 1 (D1) receptor that selectively binds to, and enhances the activity of, D1 receptors. |
| PC-49303 |
UCM-1306
D1R PAM
|
UCM-1306 (UCM1306) is a subtype-selective, non-covalent, orally bioavailable positive allosteric modulator of dopamine D1 receptor with EC50 of 60 nM. |
