| Cat. No. |
Product Name |
Information |
| PC-63187 |
Brilaroxazine
Dopamine/5-HT modulator
|
RP-5063 (Brilaroxazine) is a multimodal dopamine and serotonin modulator with partial agonist activity at DA D2, D3, D4, 5-HT1A, and 5-HT2ARs, and antagonist activity at 5-HT2B, 5-HT6 and 5-HT7Rs. |
| PC-63113 |
A-68930 hydrochloride
D1DR agonist
|
A-68930 is a potent, specific, orally bioavailable agonist of the D1 dopamine receptor (D1DR) with EC50 of 2.5 nM. |
| PC-62128 |
ML398
D4R inhibitor
|
ML398 (CID72737723) is a potent, selective, highly brain penetrant dopamine 4 (D4R) receptor antagonist with IC50/Ki of 130 nM/60 nM. |
| PC-61749 |
Alizapride hydrochloride
D2R antagonist
|
Alizapride (MS 5080) is a dopamine D2 antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting.. |
| PC-61748 |
Alizapride
D2R antagonist
|
Alizapride (MS 5080) is a dopamine D2 antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting. |
| PC-61553 |
JNJ-37822681
D2R antagonist
|
JNJ-37822681 is a potent, specific and fast-dissociating dopamine D2 antagonist with Ki of 158 nM. |
| PC-61108 |
PF-4363467
|
PF-4363467 (PF 04363467) is a novel highly potent, brain penetrant dopamine D3/D2 receptor antagonist with Ki of 1.3/692 nM respectively, with high selectivity for D3R versus other biogenic amine receptors. |
| PC-60744 |
GSK598809 hydrochloride
|
GSK598809 hydrochloride is a potent, selective, CNS penetrant and orally bioavailable dopamine D3 receptor antagonist with pKi of 8.9. |
| PC-60743 |
GSK598809
|
GSK598809 (GSK-598809) is a potent, selective, CNS penetrant and orally bioavailable dopamine D3 receptor antagonist with pKi of 8.9. |
| PC-60735 |
DETQ
Dopamine D1 modulator
|
DETQ is a novel potent, selective, allosteric and orally active dopamine D1 receptor potentiator with Kb of 26 nM. |
| PC-60665 |
SKF 83566 hydrobromide
Dopamine D1 inhibitor
|
SKF 83566 hydrobromide is a potent, selective dopamine D1 receptor antagonist with Ki of 0.56 nM. |
| PC-60614 |
A-412997 dihydrochloride
D4R agonist
|
A-412997 is a potent, selective dopamine D4 receptor agonist with Ki of 12.1 and 7.9 nM for rat and human D4 receptors, respectively. |
