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Chemical Structure : MLS1082
CAS No.: 883958-36-9
Catalog No.: PC-35534Not For Human Use, Lab Use Only.
MLS1082 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling (EC50=123 nM).
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MLS1082 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling (EC50=123 nM).
MLS1082 increase the affinity of dopamine for the D1 receptor with low micromolar potencies.
| M.Wt | 385.467 | |
| Formula | C24H23N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-cyclohexyl-10-methyl-3-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione |
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1. Luderman KD, et al. Mol Pharmacol. 2018 Aug 1. pii: mol.118.113175.
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