| Cat. No. |
Product Name |
Information |
| PC-47104 |
BAK4-54
D3R antagonist
|
BAK4-54 is a high affinity dopamine D3 receptor (D3R) antagonist/partial agonist withIC50 of 8.0 nM as full D3R antagonist, EC50 of 140 nM as partial D3R agonist. |
| PC-47103 |
CAB2-015
D3R antagonist
|
CAB2-015 is a high affinity dopamine D3 receptor (D3R) antagonist/partial agonist withIC50 of 7.4 nM, Ki of 0.351 nM, 45-fold selectivity over D2R. |
| PC-47102 |
(±)VK4-40
D3R agonist
|
(±)VK4-40 is a highly selective and metabolically stable D3 partial agonist, shows high affinity for D3 receptor (Ki=0.35 nM) and high selectivity for D3 over the D2 receptor. |
| PC-47101 |
R-VK4-40
D3R antagonist
|
R-VK4-40 is a highly selective, potent and orally available dopamine D3 receptor (D3R) antagonist with Ki of 6.8 nM, >1500-dold selectivity over D2R. |
| PC-47096 |
F17464
D3R antagonist
|
F17464 is a dopamine D 3 receptor preferential antagonist exhibiting high affinity for human dopamine receptor subtype 3 (hD3) (Ki=0.17 nM) and 5-HT1a (Ki=0.16 nM) and a >50 fold lower affinity for the human dopamine receptor subtype 2 short and long form (hD2s/l) (Ki=8.9 and 12.1 nM, respectively). |
| PC-38703 |
ML321
D2R antagonist
|
ML321, CAS 1596117-75-7, ML 321, D2R antagonist. ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity. |
| PC-38472 |
cis-(Z)-Flupentixol Dihydrochloride
Dopamine antagonist
|
cis-(Z)-Flupenthixol dihydrochloride is a dopamine receptor antagonist with antipsychotic effect, is a powerful antagonist of both D1 and D2 dopamine receptors. |
| PC-38470 |
WW-III-55
D3R agonist
|
WW-III-55 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 20 nM, exhibits >800-fold binding selectivity for D3R compared with the D2R. |
| PC-38469 |
OS-3-106
D3R agonist
|
OS-3-106 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 0.2 nM, exhibits 115-fold binding selectivity for D3R compared with the D2R. |
| PC-73068 |
LY3154207
Dopamine D1 PAM
|
LY3154207 (Mevidalen, LY-3154207) is a potent, and subtype selective human dopamine D1 positive allosteric modulator (PAM) with EC50 of 3.0 nM. |
| PC-72281 |
Trazpiroben
D2/D3 antagonist
|
Trazpiroben (TAK-906) is a potent, peripherally selective D2/D3 dopamine receptor antagonist, moderate affinity for D4, and minimal for D1 and D5. |
| PC-72176 |
(-)-IHCH7041
DRD2 agonist
|
(–)-IHCH7041 is a potent, selective partial agonist at DRD2/3 and 5-HT1AR, with EC50 of 1.38 nM in Gαi1–γ9 dissociation and 2.75 nM in β-arrestin2 recruitment assays, with negligible 5-HT2AR binding (>100-fold selectivity). |
