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Chemical Structure : WW-III-55
Catalog No.: PC-38470Not For Human Use, Lab Use Only.
WW-III-55 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 20 nM, exhibits >800-fold binding selectivity for D3R compared with the D2R.
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WW-III-55 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 20 nM, exhibits >800-fold binding selectivity for D3R compared with the D2R.
WW-III-55 (0-5.6 mg/kg) reduced cocaine self-administration, also reduced responding for sucrose and locomotor activity.
WW-III-55 attenuated yawning induced by low doses of 7-OH-DPAT (a D3R-mediated behavior).
WW-III-55 (10 mg/kg) inhibited the head twitch response (HTR) by 95% in DBA/2J mice.
| M.Wt | 449.613 | |
| Formula | C26H31N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Timothy H C Cheung, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):410-23.
2. Rangel-Barajas C, et al. Neuropharmacology. 2015 Jun;93:179-90.
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