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ML321

Chemical Structure : ML321

CAS No.: 1596117-75-7

ML321 (ML 321)

Catalog No.: PC-38703Not For Human Use, Lab Use Only.

ML321, CAS 1596117-75-7, ML 321, D2R antagonist. ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity.

Physicochemical Properties

M.Wt 410.506
Formula C21H18N2O3S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

10-Methyl-11-oxo-N-(2-(thiophen-2-yl)ethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide 5-(S)-oxide

References

1. Ashley N Nilson, et al. FASEB J. 2022 May;36 Suppl 1.

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