ML321 | D2R antagonist | Probechem Biochemicals

Chemical Structure : ML321

ML321 (ML 321)

Catalog No.: PC-38703Not For Human Use, Lab Use Only.

ML321, CAS 1596117-75-7, ML 321, D2R antagonist. ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity.

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Biological Activity

ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity.

Physicochemical Properties

M.Wt	410.506
Formula	C21H18N2O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	10-Methyl-11-oxo-N-(2-(thiophen-2-yl)ethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide 5-(S)-oxide

References

1. Ashley N Nilson, et al. FASEB J. 2022 May;36 Suppl 1.

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ML321 (ML 321)

Biological Activity

Physicochemical Properties

References

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