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ML321

Chemical Structure : ML321

CAS No.: 1596117-75-7

ML321 (ML 321)

Catalog No.: PC-38703Not For Human Use, Lab Use Only.

ML321, CAS 1596117-75-7, ML 321, D2R antagonist. ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity.

    Physicochemical Properties

    M.Wt 410.506
    Formula C21H18N2O3S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    10-Methyl-11-oxo-N-(2-(thiophen-2-yl)ethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide 5-(S)-oxide

    References

    1. Ashley N Nilson, et al. FASEB J. 2022 May;36 Suppl 1.

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