Catalog No.: PC-38469Not For Human Use, Lab Use Only.
OS-3-106 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 0.2 nM, exhibits 115-fold binding selectivity for D3R compared with the D2R.
OS-3-106 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 0.2 nM, exhibits 115-fold binding selectivity for D3R compared with the D2R.
OS-3-106 is also a partial agonist at the D2R (47% of quinpirole).
OS-3-106 (10 mg/kg) reduced cocaine self-administration, also reduced responding for sucrose and locomotor activity.
OS-3-106 attenuated yawning induced by low doses of 7-OH-DPAT (a D3R-mediated behavior).
