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Chemical Structure : OS-3-106
CAS No.: 1580000-17-4
Catalog No.: PC-38469Not For Human Use, Lab Use Only.
OS-3-106 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 0.2 nM, exhibits 115-fold binding selectivity for D3R compared with the D2R.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $448 | In stock | |
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| 1 g | Get quote |
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OS-3-106 is a high-affinity, selective dopamine D3 receptor (D3R) partial agonist with Ki value of 0.2 nM, exhibits 115-fold binding selectivity for D3R compared with the D2R.
OS-3-106 is also a partial agonist at the D2R (47% of quinpirole).
OS-3-106 (10 mg/kg) reduced cocaine self-administration, also reduced responding for sucrose and locomotor activity.
OS-3-106 attenuated yawning induced by low doses of 7-OH-DPAT (a D3R-mediated behavior).
| M.Wt | 450.60 | |
| Formula | C25H30N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-[4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl]-4-(4-thiazolyl)benzamide |
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1. Timothy H C Cheung, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):410-23.
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