| Cat. No. |
Product Name |
Information |
| PC-45173 |
Pramipexole dihydrochloride
Dopamine receptor agonist
|
Pramipexole dihydrochloride is a partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively. |
| PC-46022 |
Rotigotine hydrochloride
Dopamine receptor agonist
|
Rotigotine hydrochloride is a non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM), has 10-fold selectivity for the D3 receptor over the D2, D4, and D5 receptors and 100-fold selectivity for the D3 receptor over the D1 receptor. |
| PC-45959 |
Rotigotine
Dopamine receptor agonist
|
Rotigotine is a non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM), has 10-fold selectivity for the D3 receptor over the D2, D4, and D5 receptors and 100-fold selectivity for the D3 receptor over the D1 receptor. |
| PC-44374 |
rac-Rotigotine hydrochloride
Dopamine receptor agonist
|
rac-Rotigotine hydrochloride is a non-selective agonist of the dopamine D3 receptor (Ki=0.71 nM), has 10-fold selectivity for the D3 receptor over the D2, D4, and D5 receptors and 100-fold selectivity for the D3 receptor over the D1 receptor. |
| PC-28317 |
S33084
D3R antagonist
|
S33084 is a potent, selective dopamine D3 receptor (D3R) antagonist with pKi of 9.2 (hD2), displays >100-fold selectivity over D4. |
| PC-28316 |
Nafadotride
D3R antagonist
|
Nafadotride is a selective dopamine D3 receptor (D3R) antagonist, displays a high affinity for dopamine D2 and D3 receptors, but a low affinity for doparnine D1 and D4. |
| PC-28315 |
L-741626
D2R antagonist
|
L-741626 is a potent, selective dopamine D2 receptor (D2R, DRD2) antagonist with Ki of 2.4 nM, shows 45-80 fold selectivity over D3 and D4 receptors. |
| PC-28243 |
Chlorpromazine hydrochloride
D2R antagonist, Endocytosis inhibitor
|
Chlorpromazine hydrochloride (CPZ) is a phenothiazine antipsychotic that acts as a competitive antagonist at the D2 receptor, also exhibits antagonist activity at serotonin (5-HT) receptors 5-HT2A and 5-HT2C receptors also inhibits clathrin-mediated endocytosis. |
| PC-28242 |
Chlorpromazine
D2R antagonist, Endocytosis inhibitor
|
Chlorpromazine (CPZ) is a phenothiazine antipsychotic that acts as a competitive antagonist at the D2 receptor, also exhibits antagonist activity at serotonin (5-HT) receptors 5-HT2A and 5-HT2C receptors also inhibits clathrin-mediated endocytosis. |
| PC-27962 |
Benperidol
D2R antagonist
|
Benperidol is a potent butyrophenone antipsychotic with high affinity for the D2 dopamine receptor with Ki of 1-2 nM, selective over other dopamine and serotonin receptor subtypes, an antagonist of dopamine D2 receptor (D2R). |
| PC-27837 |
(R)-BAK2-66
D3R antagonist
|
(R)-BAK2-66 is a potent, selective dopamine D3 receptor (D3R) antagonist with Ki of 6.9 nM, >100-fold more selective for D3R over D2R. |
| PC-27835 |
BP897 hydrochloride
D3R agonist
|
BP897 hydrochloride (BP 897) is a selective D3 dopamine receptor (D3R) partial agonist with Ki of 0.92 nM and 60 nM for D3R and D2R, reduces cocaine-seeking. |
