L-741626 | D2R antagonist | Probechem Biochemicals

Chemical Structure : L-741626

CAS No.: 81226-60-0

Catalog No.: PC-28315Not For Human Use, Lab Use Only.

L-741626 is a potent, selective dopamine D2 receptor (D2R, DRD2) antagonist with Ki of 2.4 nM, shows 45-80 fold selectivity over D3 and D4 receptors.

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Biological Activity

L-741626 is a potent, selective dopamine D2 receptor (D2R, DRD2) antagonist with Ki of 2.4 nM, shows 45-80 fold selectivity over D3 and D4 receptors.

M.Wt	340.85
Formula	C20H21ClN2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol

1. Bowery BJ, et al. Br J Pharmacol. 1996 Dec;119(7):1491-7.

2. Canales JJ, et al. Pharmacol Biochem Behav. 2000 Sep;67(1):161-8.