Nafadotride

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Chemical Structure : Nafadotride

Catalog No.: PC-28316Not For Human Use, Lab Use Only.

Nafadotride is a selective dopamine D3 receptor (D3R) antagonist, displays a high affinity for dopamine D2 and D3 receptors, but a low affinity for doparnine D1 and D4.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Nafadotride is a selective dopamine D3 receptor (D3R) antagonist, displays a high affinity for dopamine D2 and D3 receptors, but a low affinity for doparnine D1 and D4.

Physicochemical Properties

M.Wt	365.48
Formula	C22H27N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-2-naphthalenecarboxamide

References

1. Sautel F, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1239-46.

2. Parsons LH, et al. J Neurochem. 1996 Sep;67(3):1078-89.

3. Levant B, et al. Neuropsychopharmacology. 1999 Aug;21(2):304-11.

4. Bordet R, et al. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3363-7.

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Nafadotride

Biological Activity

Physicochemical Properties

References

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