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Chlorpromazine

Chemical Structure : Chlorpromazine

CAS No.: 50-53-3

Chlorpromazine (CPZ)

Catalog No.: PC-28242Not For Human Use, Lab Use Only.

Chlorpromazine (CPZ) is a phenothiazine antipsychotic that acts as a competitive antagonist at the D2 receptor, also exhibits antagonist activity at serotonin (5-HT) receptors 5-HT2A and 5-HT2C receptors also inhibits clathrin-mediated endocytosis.

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Biological Activity

Chlorpromazine (CPZ) is a phenothiazine antipsychotic that acts as a competitive antagonist at the D2 receptor, also exhibits antagonist activity at serotonin (5-HT) receptors 5-HT2A and 5-HT2C receptors also inhibits clathrin-mediated endocytosis.

Physicochemical Properties

M.Wt 318.86
Formula C17H19ClN2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Phenothiazine, 2-chloro-10-[3-(dimethylamino)propyl]-

References

1. Lisanti MP, et al. Eur J Biochem. 1982 Jan;121(3):617-22.

2. Orlandi PA, et al. J Cell Biol. 1998 May 18;141(4):905-15.

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