S33084 | D3R antagonist | Probechem Biochemicals

Chemical Structure : S33084

Catalog No.: PC-28317Not For Human Use, Lab Use Only.

S33084 is a potent, selective dopamine D3 receptor (D3R) antagonist with pKi of 9.2 (hD2), displays >100-fold selectivity over D4.

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Biological Activity

S33084 is a potent, selective dopamine D3 receptor (D3R) antagonist with pKi of 9.2 (hD2), displays >100-fold selectivity over D4.

M.Wt	451.57
Formula	C29H29N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-((3aR,9bS)-8-cyano-1,3a,4,9b-tetrahydrochromeno[3,4-c]pyrrol-2(3H)-yl)butyl)-[1,1'-biphenyl]-4-carboxamide

1. Millan MJ, et al. J Pharmacol Exp Ther. 2004 Jun;309(3):903-20.

2. Dubuffet T, et al. Bioorg Med Chem Lett. 1999 Jul 19;9(14):2059-64.

3. Cussac D, et al. Eur J Pharmacol. 2000 Apr 7;394(1):47-50.