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Chemical Structure : Pramipexole dihydrochloride
CAS No.: 104632-25-9
Catalog No.: PC-45173Not For Human Use, Lab Use Only.
A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $128 | In stock |
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A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively; also possesses low/insignificant affinity (500–10,000 nM) for the 5-HT1A, 5-HT1B, 5-HT1D, and α2-adrenergic receptors; used for treating Parkinson's disease (PD) and restless legs syndrome (RLS).
Parkinson's Disease
Approved
| M.Wt | 284.249 | |
| Formula | C10H19Cl2N3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, hydrochloride (1:2), (6S)- |
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1. Newman-Tancredi A, et al. J Pharmacol Exp Ther. 2002 Nov;303(2):805-14.
2. Kvernmo T, et al. Clin Ther. 2006 Aug;28(8):1065-78.
3. Millan MJ, et al. J Pharmacol Exp Ther. 2002 Nov;303(2):791-804.
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