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Chemical Structure : PF-06256142
Catalog No.: PC-35799Not For Human Use, Lab Use Only.
PF-06256142 (PF06256142) is a potent and selective orthosteric agonist of the D1 receptor with EC50 (cAMP) of 33 nM, shows exquisitely selectivity over D2.
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PF-06256142 (PF06256142) is a potent and selective orthosteric agonist of the D1 receptor with EC50 (cAMP) of 33 nM, shows exquisitely selectivity over D2.
PF-06256142 demonsrates reduced receptor desensitization relative to dopamine and other catechol-containing agonists.
| M.Wt | 356.385 | |
| Formula | C21H16N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Davoren JE, et al. J Med Chem. 2018 Nov 15. doi: 10.1021/acs.jmedchem.8b01622.
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