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Chemical Structure : Compound 621433144
Catalog No.: PC-36061Not For Human Use, Lab Use Only.
Compound 621433144 (ZINC000621433144, Z3269026405) is a potent, selective full agonist of the D4 receptor with 2,500-fold subtype selectivity.
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Compound 621433144 (ZINC000621433144, Z3269026405) is a potent, selective full agonist of the D4 receptor with 2,500-fold subtype selectivity; Compound 621433144 was also functionally selective, with a 17-fold bias towards Gi signalling versus β-arrestin recruitment, compared to the characteristic agonist quinpirole.
| M.Wt | 301.434 | |
| Formula | C18H27N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lyu J, et al. Nature. 2019 Feb 6. doi: 10.1038/s41586-019-0917-9.
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