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Chemical Structure : LY3154885
Catalog No.: PC-38113Not For Human Use, Lab Use Only.
LY 3154885 is a potent dopamine D1 receptor positive allosteric modulator (PAM) with EC50 of 11.7 nM.
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LY 3154885 is a potent dopamine D1 receptor positive allosteric modulator (PAM) with EC50 of 11.7 nM.
LY 3154885 displays reduced the CYP3A4-mediated victim drug-drug interactions (DDI) risk.
LY 3154885 possesses similar in vitro and in vivo pharmacologic properties as Mevidalen (LY 3154207), but is metabolized mainly by UGT.
| M.Wt | 444.356 | |
| Formula | C23H23Cl2N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Junliang Hao, et al. J Med Chem. 2022 Mar 10;65(5):3786-3797.
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