Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Dopamine Receptor-LY3154885
LY3154885

Chemical Structure : LY3154885

CAS No.: 2379422-72-5

Add to Favorites

LY3154885 (LY 3154885)

Catalog No.: PC-38113Not For Human Use, Lab Use Only.

LY 3154885 is a potent dopamine D1 receptor positive allosteric modulator (PAM) with EC50 of 11.7 nM.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    LY 3154885 is a potent dopamine D1 receptor positive allosteric modulator (PAM) with EC50 of 11.7 nM.
    LY 3154885 displays reduced the CYP3A4-mediated victim drug-drug interactions (DDI) risk.
    LY 3154885 possesses similar in vitro and in vivo pharmacologic properties as Mevidalen (LY 3154207), but is metabolized mainly by UGT.

    Physicochemical Properties

    M.Wt 444.356
    Formula C23H23Cl2N3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl)-1-methyl-5-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one

    References

    1. Junliang Hao, et al. J Med Chem. 2022 Mar 10;65(5):3786-3797.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: