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Chemical Structure : PF-592379
Catalog No.: PC-60216Not For Human Use, Lab Use Only.
PF-592379 is a potent, selective, orally active agonist of dopamine D3 receptor with EC50 of 21 nM.
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PF-592379 is a potent, selective, orally active agonist of dopamine D3 receptor with EC50 of 21 nM.
PF-592379 displays >470 and 180-fold functional selectivity over D2 and D4 dopamine receptors, respectively.
PF-592379 demonstrates activity in animal models of male erectile dysfunction.
| M.Wt | 235.331 | |
| Formula | C13H21N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Attkins N, et al. Xenobiotica. 2010 Nov;40(11):730-42.
2. Collins GT, et al. Behav Pharmacol. 2012 Jun;23(3):280-91.
3. Thomsen M, et al. J Pharmacol Exp Ther. 2017 Jul;362(1):161-176.
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