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SKF-82958 hydrobromide

Chemical Structure : SKF-82958 hydrobromide

CAS No.: 74115-01-8

SKF-82958 hydrobromide ((±)-SKF 82958 hydrobromide;Chloro-APB hydrobromide)

Catalog No.: PC-42584Not For Human Use, Lab Use Only.

SKF-82958 hydrobromide is a potent, full dopamine D1 agonist, produces characteristic anorectic effects, hyperactivity and self-administration in animals.

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Biological Activity

SKF-82958 hydrobromide is a potent, full dopamine D1 agonist, produces characteristic anorectic effects, hyperactivity and self-administration in animals.
SKF-82958 hydrobromide also is a subtype-selective estrogen receptor-alpha (ERalpha ) agonist.

Physicochemical Properties

M.Wt 410.7325
Formula C19H21BrClNO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 102.5 mg/mL; H2O: < 6 mg/mL

Chemical Name/SMILES

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1)

References

1. Pfeiffer FR, et al. J Med Chem. 1982 Apr;25(4):352-8.

2. Walters MR, et al. J Biol Chem. 2002 Jan 18;277(3):1669-79.

3. O'Boyle KM, et al. Neuropharmacology. 1989 Apr;28(4):401-5.

4. Steulet AF, et al. Eur J Pharmacol. 1990 Nov 20;191(1):19-27.

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