Metoclopramide |CAS:364-62-5 Probechem Biochemicals

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Chemical Structure : Metoclopramide

CAS No.: 364-62-5

Metoclopramide

Catalog No.: PC-45204Not For Human Use, Lab Use Only.

Metoclopramide is apotent dopamine D2 receptor antagonist with Ki of 28 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Metoclopramide is apotent dopamine D2 receptor antagonist with Ki of 28 nM.
Metoclopramide also is a mixed 5-HT3 receptor antagonist/5-HT4 receptor agonist.
Metoclopramide is commonly used to treat nausea and vomiting caused by chemotherapy.

Physicochemical Properties

M.Wt	299.7964
Formula	C14H22ClN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 41 mg/mL
Chemical Name/SMILES	Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-

References

1. Matsui A, et al. J Pharmacol Exp Ther. 1998 Nov;287(2):725-32.

2. Tonini M, et al. Pharmacol Res. 1995 May;31(5):257-60.

3. Bateman DN, et al. Br J Clin Pharmacol. 1978 Nov;6(5):401-7.

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Metoclopramide

Biological Activity

Physicochemical Properties

References

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