FOB02-04A

Chemical Structure : FOB02-04A

Catalog No.: PC-23118Not For Human Use, Lab Use Only.

FOB02-04A is a selective, bitopic and full agonist of dopamine 3 receptor (D3R) with Ki of 1.85 nM, 47- and 155-fold selective over D2R and D4R.

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Biological Activity

FOB02-04A is a selective, bitopic and full agonist of dopamine 3 receptor (D3R) with Ki of 1.85 nM, 47- and 155-fold selective over D2R and D4R.

M.Wt	433.56
Formula	C25H31N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-((1R,2S)-2-(((2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholino)methyl)cyclopropyl)ethyl)-1H-indole-2-carboxamide

1. Arroyo-Urea S, et al. Nat Commun. 2024 Sep 5;15(1):7759.

2. Battiti FO, et al. ACS Med Chem Lett. 2020 Feb 28;11(10):1956-1964.

3. Battiti FO, et al. J Med Chem. 2019, 62 (13), 6287–6314.