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FOB02-04

Chemical Structure : FOB02-04

CAS No.: 2363162-62-1

FOB02-04 (FOB 02-04)

Catalog No.: PC-22633Not For Human Use, Lab Use Only.

FOB02-04 is a potent, selective dopamine D3 receptor (D3R) agonist with Ki of 2.84 nM, weak affinity with Ki of 106 nM for D2R.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FOB02-04 is a potent, selective dopamine D3 receptor (D3R) agonist with Ki of 2.84 nM, weak affinity with Ki of 106 nM for D2R.
FOB02-04 significantly reduced impulsive choices in high-impulsive rats but had no effects in low-impulsive rats.

Physicochemical Properties

M.Wt 433.56
Formula C25H31N5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

trans-N-(2-(2-(((2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholino)methyl)cyclopropyl)ethyl)-1H-indole-2-carboxamide

References

1. Battiti FO, et al. J Med Chem. 2019 Jul 11;62(13):6287-6314.

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