LB-102 | D(2/3)/5-HT(7) inhibitor | Probechem Biochemicals

Chemical Structure : LB-102

LB-102 (LB102)

Catalog No.: PC-23209Not For Human Use, Lab Use Only.

LB-102 is an N-methylated analogue of amisulpride, selective dopamine D(2/3)/5-HT(7) inhibitor, binds to the D2 receptor and 5-HT7 receptor with Ki of 0.85 nM and 31 nM respectively, shows potential for treatment of schizophrenia and other psychiatric disorders.

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Biological Activity

Physicochemical Properties

M.Wt	383.51
Formula	C18H29N3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxy-4-(methylamino)benzamide

References

1. Biernat L, et al. Psychopharmacology (Berl). 2022 Sep;239(9):3009-3018.

2. Grattan V, et al. ACS Omega. 2019 Aug 15;4(9):14151-14154.

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LB-102 (LB102)

Biological Activity

Physicochemical Properties

References

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