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Fenoldopam mesylate

Chemical Structure : Fenoldopam mesylate

CAS No.: 67227-57-0

Fenoldopam mesylate (SKF-82526, SKF82526)

Catalog No.: PC-23532Not For Human Use, Lab Use Only.

Fenoldopam (SKF82526) is a potent, selective dopamine-1 (DA-1) receptor partial agonist with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Fenoldopam (SKF82526) is a potent, selective dopamine-1 (DA-1) receptor partial agonist with EC50 of 55.5 nM in stimulating cAMP accumulation in LLC-PK1 cells.
Fenoldopam (SKF82526) blocks by the DA1-selective antagonist Sch 23390.
Fenoldopam (SKF82526) is a potent, selective, orally active renal vasodilator which acts, at least in part, through stimulation of renal vascular dopamine receptors and is without significant effect on central dopamine receptors after systemic administration.
Fenoldopam (SKF82526) shows potent renal vasodilating properties.

Physicochemical Properties

M.Wt 305.76
Formula C16H16ClNO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-chloro-7,8-dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-(1H)-3-benzazepine

References

1. Hahn RA, et al. J Pharmacol Exp Ther. 1982 Nov;223(2):305-13.

2. Carey RM, et al. J Clin Invest. 1984 Dec;74(6):2198-207.

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