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Raclopride

Chemical Structure : Raclopride

CAS No.: 84225-95-6

Raclopride (FLA 870)

Catalog No.: PC-22235Not For Human Use, Lab Use Only.

Raclopride (FLA 870) is a potent, selective dopamine D2/D3 receptor antagonist, binds to D2 and D3 receptors with Ki of 1.8 nM and 3.5 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Raclopride (FLA 870) is a potent, selective dopamine D2/D3 receptor antagonist, binds to D2 and D3 receptors with Ki of 1.8 nM and 3.5 nM, respectively.
Raclopride (FLA 870) displays >150-fold selectivity over D1 and D4 receptors.
Raclopride (FLA 870) shows potential antipsychotic effects.

Physicochemical Properties

M.Wt 347.24
Formula C15H20Cl2N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide

References

1. Köhler C, et al. Biochem Pharmacol. 1985 Jul 1;34(13):2251-9.

2. Farde L, et al. Proc Natl Acad Sci U S A. 1985 Jun;82(11):3863-7.

3. Seeman P, et al. Trends Pharmacol Sci. 1994 Jul;15(7):264-70.

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