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PW0464

Chemical Structure : PW0464

CAS No.: 1643462-93-4

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PW0464 ((Rac)-Razpipadon)

Catalog No.: PC-23108Not For Human Use, Lab Use Only.

PW0464 ((Rac)-Razpipadon) is a potent, selective G protein biased ligand/agonist of dopamine 1 receptor (D1R) with EC50 of 5.8 nM (Gs-cAMP), Emax of 104%.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PW0464 ((Rac)-Razpipadon) is a potent, selective G protein biased ligand/agonist of dopamine 1 receptor (D1R) with EC50 of 5.8 nM (Gs-cAMP), Emax of 104%.

Physicochemical Properties

M.Wt 389.36
Formula C19H17F2N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,4(1H,3H)-Pyrimidinedione, 6-[4-[[3-(difluoromethoxy)-2-pyridinyl]oxy]-2-methylphenyl]-1,5-dimethyl-

References

1. Wang P, et al. ACS Med Chem Lett. 2019 Apr 5;10(5):792-799.

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