D5R agonist 5j

Chemical Structure : D5R agonist 5j

Catalog No.: PC-23109Not For Human Use, Lab Use Only.

D5R agonist 5j is a selective dopamine D5 receptor (D5R) partial agonist with EC50 of 269.7 nM, not active at the other four dopamine receptors.

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Biological Activity

D5R agonist 5j is a selective dopamine D5 receptor (D5R) partial agonist with EC50 of 269.7 nM, not active at the other four dopamine receptors.
D5R agonist 5j readily crosses the BBB and enhances the cognition in the scopolamine-induced amnesia model.

Physicochemical Properties

M.Wt	463.28
Formula	C19H18IN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-iodophenyl)-6-(2,4,5-trimethoxyphenyl)pyrimidin-2-amine

References

1. Sakesh Kumar, et al. Bioorg Chem. 2024 Sep 7:153:107809.

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D5R agonist 5j

Biological Activity

Physicochemical Properties

References

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