Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Dopamine Receptor-SB-277011 hydrochloride
SB-277011 hydrochloride

Chemical Structure : SB-277011 hydrochloride

CAS No.: 215804-67-4

SB-277011 hydrochloride (SB277011A hydrochloride)

Catalog No.: PC-23120Not For Human Use, Lab Use Only.

SB-277011 hydrochloride (SB277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0.

Packing Price Stock Quantity
10 mg $128 In stock
25 mg $218 In stock
50 mg $368 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SB-277011 hydrochloride (SB277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0.
SB-277011 displays >100-fold selectivity against the D2, 5-HT1B, and 5-HT1D receptors.
SB-277011 exhibits high oral bioavailability and brain penetration in rats.

Physicochemical Properties

M.Wt 475.03
Formula C28H31ClN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((1r,4r)-4-(2-(6-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)quinoline-4-carboxamide hydrochloride

References

1. Stemp G, et al. J Med Chem. 2000 May 4;43(9):1878-85.

2. Reavill C, et al. J Pharmacol Exp Ther. 2000 Sep;294(3):1154-65.

3. Ashby CR Jr, et al. J Pharmacol Exp Ther. 2000 Sep;294(3):1166-74.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: