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Cariprazine hydrochloride

Chemical Structure : Cariprazine hydrochloride

CAS No.: 1083076-69-0

Cariprazine hydrochloride (RGH188 hydrochloride)

Catalog No.: PC-24330Not For Human Use, Lab Use Only.

Cariprazine (RGH-188) hydrochloride is an antipsychotic compound that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cariprazine (RGH-188) hydrochloride is an antipsychotic compound that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).

Physicochemical Properties

M.Wt 463.87
Formula C21H33Cl3N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(trans-4-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1,1-dimethylurea hydrochloride

References

1. Seneca N, et al. Psychopharmacology (Berl). 2011 Dec;218(3):579-8

2. Kiss B, et al. J Pharmacol Exp Ther. 2010 Apr;333(1):328-40.

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