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PG01037

Chemical Structure : PG01037

CAS No.: 790658-27-4

PG01037 (PG 01037)

Catalog No.: PC-20862Not For Human Use, Lab Use Only.

PG01037 is a potent selective dopamine D3 receptor (D3R) antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PG01037 is a potent selective dopamine D3 receptor (D3R) antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively.

    Physicochemical Properties

    M.Wt 481.42
    Formula C26H26Cl2N4O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)but-2-en-1-yl)-4-(pyridin-2-yl)benzamide

    References

    1. Grundt P, et al. J Med Chem. 2007 Aug 23;50(17):4135-46.

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