PG01037 | D3 receptor antagonist | Probechem Biochemicals

Chemical Structure : PG01037

PG01037 (PG 01037)

Catalog No.: PC-20862Not For Human Use, Lab Use Only.

PG01037 is a potent selective dopamine D3 receptor antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively.

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Biological Activity

PG01037 is a potent selective dopamine D3 receptor antagonist with binding Ki of 0.7 nM, displays 133- and 540-fold selectivity over D2 and D4 receptors, respectively.

Physicochemical Properties

M.Wt	481.42
Formula	C26H26Cl2N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(NC/C=C/CN1CCN(C2=CC=CC(Cl)=C2Cl)CC1)C3=CC=C(C4=NC=CC=C4)C=C3

References

1. Grundt P, et al. J Med Chem. 2007 Aug 23;50(17):4135-46.

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PG01037 (PG 01037)

Biological Activity

Physicochemical Properties

References

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