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PF-06412562

Chemical Structure : PF-06412562

CAS No.: 1609258-91-4

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PF-06412562 (PF-2562, CVL-562)

Catalog No.: PC-23107Not For Human Use, Lab Use Only.

PF-06412562 (PF-2562, CVL-562) is a potent, selective non-catechol dopamine D1R agonist with Ki of 113 nM and EC50 of 568 nM, Emax 44%, PF-06412562 is a selective D1/D5 dopamine receptor partial agonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PF-06412562 (PF-2562, CVL-562) is a potent, selective non-catechol dopamine D1R agonist with Ki of 113 nM and EC50 of 568 nM, Emax 44%, PF-06412562 is a selective D1/D5 dopamine receptor partial agonist.

    Physicochemical Properties

    M.Wt 331.38
    Formula C19H17N5O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-[4-(4,6-Dimethyl-5-pyrimidinyl)-3-methylphenoxy]-1H-pyrazolo[4,3-c]pyridine

    References

    1. Sakesh Kumar, et al. Bioorg Chem. 2024 Sep 7:153:107809.

    2. Patent US20140128374A1..

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