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AG-0029

Chemical Structure : AG-0029

CAS No.: 1715916-58-7

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AG-0029 (AG0029)

Catalog No.: PC-20169Not For Human Use, Lab Use Only.

AG-0029 is a highly potent agonist of dopamine D2/D3 receptor (EC50=0.08 nM) and a moderate affinity antagonis of H3 receptor (IC50=111 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AG-0029 is a highly potent agonist of dopamine D2/D3 receptor (EC50=0.08 nM) and a moderate affinity antagonis of H3 receptor (IC50=111 nM).
    AG-0029 could meliorate both the motor and cognitive symptoms of parkinson's disease (PD).

    Physicochemical Properties

    M.Wt 452.56
    Formula C25H32N4O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    7-(4-(3-(4-(morpholinomethyl) phenoxy)propyl)piperazin-1-yl) benzo[d]oxazol-2(3H)-one

    References

    1. Ghazanfari N, et al. Mol Pharm. 2022 Jul 4;19(7):2287-2298.

    2. Patent WO2015069110.

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